Molecular simulations can help understand the mechanism behind drug resistance to lung cancer medications.
Scientists from the Universities of Bristol and Parma, Italy, have used molecular simulations to understand the resistance to osimertinib - an anticancer drug used to treat types of lung cancer.
bOsimertinib For Lung Cancer/b
Osimertinib binds tightly to a protein, epidermal growth factor receptor (EGFR), which is overexpressed in many tumors.
EGFR is involved in a pathway that ...
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