Epigenetic therapy that inhibited the enzyme G9a, a type of histone methyltransferase boosted cancer stem cells that are believed to drive tumors. Boston Children's Hospital scientists also discovered a strategy that reduces these cells, curbing lung cancer in mice.
Epigenetic therapies -- targeting enzymes that alter what genes are turned on or off in a cell -- are of growing interest in the cancer field as a way of making a cancer less aggressive or less malignant. Findings were published online today in Nature Communications....
Epigenetic therapy that inhibited the enzyme G9a, a type of histone methyltransferase boosted cancer stem cells that are believed to drive tumors. Boston Children's Hospital scientists also discovered a strategy that reduces these cells, curbing lung cancer in mice.
Epigenetic therapies -- targeting enzymes that alter what genes are turned on or off in a cell -- are of growing interest in the cancer field as a way of making a cancer less aggressive or less malignant. Findings were published online today in Nature Communications....