The pathway for treatment-resistant lung cancer has been discovered by scientists at the Medical College of Georgia and Georgia Cancer Center at Augusta University.
Scientists have found a first step appears to be lung cancer cells expressing high levels of the molecule TIMP-1, classically considered a tumor inhibitor but at high levels already associated with a poor prognosis for patients. TIMP-1 then turns up expression of the immune system modulator IL-6, which is already associated with resistance to cancer chemotherapy....
The pathway for treatment-resistant lung cancer has been discovered by scientists at the Medical College of Georgia and Georgia Cancer Center at Augusta University.
Scientists have found a first step appears to be lung cancer cells expressing high levels of the molecule TIMP-1, classically considered a tumor inhibitor but at high levels already associated with a poor prognosis for patients. TIMP-1 then turns up expression of the immune system modulator IL-6, which is already associated with resistance to cancer chemotherapy....