High AIM2 Inflammasomes Seen in COPD Lung Cancer Patients

Cigarette smoking is the leading risk factor for COPD and lung cancer establishment, as per the iOncotarget's/i study "Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma". Researchers exposed mice to nose-only cigarette smoke to mimic COPD and used human samples of lung adenocarcinoma patients according to the smoking and COPD status. Higher expression of AIM2 in non-cancerous tissue of smoking COPD adenocarcinoma patients was correlated to a ...