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Histone Demethylase Associated With Non-Small Cell Lung Cancer

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One of the leading causes of cancer deaths worldwide is Non-small cell lung cancer (NSCLC). Current therapies that target cellular kinases have been effective for some patients. However, many individuals with NSCLS do not respond. Recent studies of other cancers indicate that the global changes in DNA methylation patterns may drive tumor formation. In this issue of the iJournal of Clinical Investigation/i, MinGyu Lee and colleagues at MD Anderson Cancer Center evaluated histone methylation ...

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